天然产物的提取、分离、结构表征及活性研究、药物质量控制及质量标准研究、色谱分析方法的开发及完善。

近年发表的科研论文

（1）Wei Wu , Yuhan Shi , Jingya Liu,  Xiaoyu Liu, Hao Liu, Tao Wang, Guoqi Zhang,  Zhihong Xu*，Carbon dots derived from expired drugs based ratiometric fluorescent sensor for horseradish peroxidase in fruits and vegetables and screening inhibitorsm Microchimica Acta (2024) 191:109, https://doi.org/10.1007/s00604-023-06160-9.（Q2）

（2）  Guo-Qi Zhang , Wei-ping Liu,  Yu-Han Shi , Yu-xian Zou, Li-Yao Xu, Hui-Ling Cheng, Tao Wang, Wen-bin Li, Yan Zhao , Zhi-Hong Xu*，Intrinsic peroxidase activity of carbon dots derived from expired drugs and its application in automatic detection of total antioxidant capacity, Microchemical Journal, 2024, 197(2024)109720, https://doi.org/10.1016/j.microc.2023.109720. （Q2）

（3）Guo-Qi Zhang , Yu-Han Shi ,Wei-Wu , Yang Zhao , Zhi-Hong Xu*，A fluorescent  carbon dots synthesized at room temperature for automatic determination of nitrite in Sichuan pickles, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy，2023，286 (2023) 12205，https://doi.org/10.1016/j.saa.2022.12205. （Q2）

（4）Jingya Liu^α, Li Li^α, Wei Wu, Guoqi Zhang, Yinqiu Zheng, Chenrui Ma, Wen Li, Yujie Yan, Zhihong Xu*，Green extraction of active ingredients from finger citron using subcritical water and assessment of antioxidant activity，2023,  Industrial Crops & Products 200 (2023) 116821,https://doi.org/10.1016/j.indcrop.2023.116821.（Q1）

（5）Jingya Liu^α, Yinqiu Zheng^α, Shuang Dai, Li Li, Wei Wu, Rong Gou, Deyuan Wang, Shiyu Long, Meihua Huang, Zhihong Xu*，In vitro Activity of Picroside I in Type 2 Diabetes Based on Oxidative Stress，2023,  J. Mex. Chem. Soc. 2023, 67(2): 130-142, http://doi.org/10.29356/jmcs.v67i2.1899.（Q4）

（6）Xiaojun Luo, Shutong Zhang, Zhichao Xia, Rui Tan, Qiuju Li, Ling Qiao, Yi He*, Guoqi Zhang**,Zhihong Xu***, A combined surface-enhanced Raman spectroscopy (SERS)/colorimetric approach for the  sensitive detection of malondialdehyde in biological samples, 2023, Analytica Chimica Acta 1241  (2023)  340803, https://doi.org/10.1016/j.aca.2023.340803.（Q1）

（7）Guo-Qi Zhang , Wei-Wu , Yu-Han Shi , Yang Zhao , Zhi-Hong Xu*，Flow injection spectrophotometric determination total antioxidant capacity in human serum samples based on response surface methodology to optimize synthesized peroxidase-like activity carbon dots，Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy，2022，284 (2023) 121832，https://doi.org/10.1016/j.saa.2022.121832.（Q2）

（8）Li Li, Shuang Dai, Jing-ya Liu, Wei Wu, Qian-xi Zhao, Xin Wang, Na Wang, and Zhi-hong Xu*, Antagonistic Effect and In Vitro Activity of Dauricine on Glucagon Receptor, Journal of Natural Products, 2022, https://doi.org/10.1021/acs.jnatprod.2c00446.（Q2）

（9）Zhihong Xu, Jinying Wu, Shuang Dai, Yuanyuan Jiang, Li Zhang, Antimicrobial activity of combined essential oils of Origanum vulgare L. and Houttuynia cordata T. against Salmonellaenteritidis and Salmonella Paratyphiβ, Journal of Food Processing and Preservation, 2022, 46 (4):1-9, https://doi.org/10.1111/fpp.16472.（Q4）

（10）Guangyou  Jiang, Min Liu, Dongmei Fang, Ping Tan, Min Huang, Taiping Zhou, Zhenju Jiang, Zhihong Xu* and Zhouyu Wang*，A base promoted one pot solvent free version of the Ramachary reductive coupling/alkylation reaction for the synthesis of 2,2-disubstituted ethyl cyanoacetates，RSC Adv., 2018, 8, 8961–8964.（Q2）

（11）Z. Xu, R. Peng, X. Chen, R. Ghosh & H. P. V. Rupasinghe, Isolation of flavonoids from apple peel using novel graphene oxide-cotton fiber，Natural Product Research, 2017,31(21):2559-2563.（Q4）

主要讲授课程：

本科生：仪器分析、分析化学、药物分析、无机及分析化学；

研究生：专业英语（化学）、高等仪器分析。

（1）2011届“优秀本科毕业论文”指导教师

（2）2013届“优秀本科毕业论文”指导教师

（3）2017届“大学生创新训练项目”（国家级）指导教师

（1）2023年指导学生参加全国大学生生命科学竞赛第八届（科学探究类）四川赛区决赛暨第二届四川省大学生“生命之星”科技竞赛，获三等奖。

（2）2014年指导学生参加“创青春”四川省大学生创新创业大赛，获银奖

（3）2012年指导学生参加“飞young青春”第七届“挑战杯”四川省大学生创业计划竞赛，获优胜奖

（4）2012年获西华大学就业工作优秀指导教师

世界中医药学会联合会(WFCMS)中药分析专业委员会会员、四川省分析测试学会理事、四川省色谱学委员会副主任委员。