致力于开发新型有机小分子荧光探针，主要应用于食品安全检测及活细胞成像研究。

【1】科研项目

(1)西华大学人才引进项目，新型β-半乳糖苷酶荧光探针的构建与应用，Z242022，2024-2026，20万元，在研，主持。

(2)国家自然科学基金委员会, 联合基金项目, U21A20308, 大Stokes位移荧光染料的设计及在手术导航中的应用, 2022-2025， 256万元, 在研, 参与。

【2】代表性学术论文：

(1) Yi-Min Shan*, Kang-Kang Yu, Kun Li, Fan-Yuan Yu, Yan-Hong Liu, Xiao-Qi Yu. Ultrasensitive two-photon probes for rapid detection of β-galactosidase in fruit softening and cellular senescence. Food Chemistry. 2024, 431, 137117-137123.(2023 IF:8.8)

(2) Yi-Min Shan*, Kang-Kang Yu, Li-Na Zhang, Si-Xian Wu, Xiao-Liang Li, Hong Zhang, Fei-Fan Xiang, Fan-Yuan Yu, Yan-Hong Liu, Xiao-Qi Yu, Kun Li, Wen-Ming Xu. Revelation of β-galactosidase variation in senile sperms and organs via a silicon xanthene near-infrared probe. Sensors and Actuators B: Chemical, 2023, 397, 134663-134670.(2023 IF:8.4)

(3) Yi-Min Shan*, Kang-Kang Yu, Nan Wang, Fan-Yuan Yu, Kun Li, Yan-Hong Liu, Xiao-Qi Yu. Assessing ClO^- level during ER stress and cellular senescence through a ratio fluorescent probe with dual organelle targeting ability. Sensors and Actuators B: Chemical, 2022, 358, 131383-131391.(2023 IF:8.4)

(4) Jin-Lin Zhou, Kun Li, Lei Shi, Hong Zhang, Hao-Yuan Wang, Yi-Min Shan*, Shan-Yong Chen, Xiao-Qi Yu, Hydrogen-bond locked purine chromophores with high photostability for lipid droplets imaging in cells and tissues. Chinese Chemical Letters, 2023, 34, 107689-107692.(2023 IF:9.1)

(5) Nan Wang, Kang-Kang Yu, Yi-Min Shan*, Kun Li, Jun Tian, Xiao-Qi Yu, and Xi Wei. HClO/ClO^--Indicative interpenetrating polymer network hydrogels as intelligent bioactive materials for wound healing. ACS Applied Bio Materials, 2020, 3 (1), 37-44.(2023 IF:4.7)

(6) Wei Zhang, Na Wang, Yuan Yu, Yi-Min Shan*, Bing Wang, Xue-Mei Pu, Xiao-Qi Yu. Synthetic Regulation of 1,4-Dihydropyridines for the AIE or AIEE Effect: From Rational Design to Mechanistic Views. Chemistry - A European Journal. 2018, 24, 4871-4878.(2023 IF:4.3)